COVID in children

As far as I know, there is no data on pediatric covid symptoms or management in the States. I know of the paper from China, but was wondering what is the user experience in this group regarding the same. I just looked at https://www.myvps.org and was surprised to see 7 intubated kids. Granted there could have been co-morbid reasons for the intubation but was a bit surprised nonetheless. What are your thoughts?

Anecdotally, there seems to be a trend towards more severe cases in younger patients as the pandemic has progressed (first pediatric death reported in the USA today).

Our team has been analyzing cases from China and we have observed several reports demonstrating a higher rate of COVID-19 in children with a history of congenital heart disease. We suspect this to be due to potentially limited cardiopulmonary reserve and alterations in ACE2 expression, which may predispose them to more symptomatic infections.

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More intubated patients in us picu as of today. Illinois reporting a infant death. Definitely seeing a bit different picture than what was observed in China.

We have a three week old, we will report soon.

Hey that’s really interesting! I haven’t seen any information re: children or adults with CHD. Is there anything you can share?

We transported a 7d old newborn. Fever, coughing, dyspnoe, tachypnoe. No follow up yet…

Hi Peta -

Here are the two case series in English that have CHD patients in their case series:

Case series of 25 children of which 2 developed critical illness (both of which had with a history of corrected CHD):
Zheng F, Liao C, Fan QH, et al. Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China. Curr Med Sci. 2020.

Case series of 20 children - 2 had a history of ASD repair, 3 arrhythmia.
Xia W, Shao J, Guo Y, Peng X, Li Z, Hu D. Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults. Pediatr Pulmonol. 2020.
https://onlinelibrary.wiley.com/doi/full/10.1002/ppul.24718

Thanks! I had missed those, but hadn’t seen details of CHD in the higher impact publications. I have to admit, I’m not sure I agree with Xia’s characterization of iRBBB and sinus tachycardia as pre-existing cardiac disease.
Appreciate the heads-up - thanks!

Update: in the 7d old child there was a incorrect positive test as we’ve been told. I have no confirmation except coleague’s words.

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