Colchicine use in COVID

Good afternoon,

Wondering if anyone has utilized colchicine to treat or prevent massive inflammatory response seen in COVID patients? I know some studies are underway but was wondering if anyone has utilized it and what their experience has been.

Sonja Damjanoski, PharmD, BCPS, BCCCP

The mechanism for Chloroquine most likely is its known side effect of preventing platelet agglutination. Therefore likely a variable response in the ICU. Prophylaxis before symptoms makes more sense for Chloroquine, for that matter baby aspirin daily prophylaxis and staying hydrated would make sense too. Once in ICU I would be strongly considering use of thrombolytics.

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